Description

(1S-Trans)-2-(4-tert-Butylphenoxy)Cyclohexanol is a chiral, substituted cyclohexanol derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and potential intermediate for the development of high-value, optically active materials. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty chemicals and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Liquid Crystal Materials: Acts as a chiral dopant or a core structural unit in the production of ferroelectric and nematic liquid crystals for display technologies.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Flavor and Fragrance Chemistry: Employed in the synthesis of complex, stereochemically defined odorants and flavor compounds.
• Academic and Industrial R&D: A valuable compound for methodological studies in stereoselective synthesis and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	(1S-Trans)-2-(4-tert-Butylphenoxy)Cyclohexanol
CAS No.	169527-71-3
Molecular Formula	C16H24O2
Molecular Weight	248.36 g/mol
Synonyms	(1S,2S)-2-(4-tert-Butylphenoxy)cyclohexanol; trans-2-(4-tert-Butylphenoxy)cyclohexanol; (1S-trans)-2-(4-(1,1-Dimethylethyl)phenoxy)cyclohexanol; 2-(p-tert-Butylphenoxy)cyclohexanol (trans-(1S)-); 4-tert-Butylphenyl trans-2-hydroxycyclohexyl ether; (1S,2S)-rel-2-(4-(1,1-Dimethylethyl)phenoxy)cyclohexanol; Chiral Cyclohexanol Derivative
EINECS	Contact for details

Quality Control

Our (1S-Trans)-2-(4-tert-Butylphenoxy)Cyclohexanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.