Description

1,8-Octanedioic-D12 Acid is a deuterium-labeled analog of suberic acid, where all twelve hydrogen atoms are replaced with the stable isotope deuterium. This high isotopic purity makes it an indispensable internal standard and tracer in quantitative mass spectrometry and metabolic research. It is primarily utilized by analytical laboratories and research institutions in the pharmaceutical, environmental, and life science sectors for precise quantification and pathway analysis.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of suberic acid and related dicarboxylic acids.
• Tracer compound in metabolic flux analysis and stable isotope labeling studies.
• Deuterated reference material for nuclear magnetic resonance (NMR) spectroscopy method development.
• Key starting material or intermediate in the synthesis of deuterated polymers or specialty chemicals.
• Use in environmental testing for the analysis of dicarboxylic acids as atmospheric aerosol markers.
• Biochemical research involving lipid metabolism and inborn errors of metabolism.

Basic Information

Product Name	1,8-Octanedioic-D12 Acid
CAS No.	169397-99-3
Molecular Formula	C8D12O4
Molecular Weight	180.27 g/mol
Synonyms	Suberic Acid-d12; Octanedioic-1,2,3,4,5,6,7,8,9,10,11,12-d12 Acid; Deuterated Suberic Acid; Perdeuterated Suberic Acid; Dodecadeuterooctanedioic Acid; 1,8-Dicarboxyoctane-d12; Cork Acid-d12
EINECS	Contact for details

Quality Control

Our 1,8-Octanedioic-D12 Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm chemical identity and isotopic purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the deuterium enrichment (typically ≥98 atom % D) and chemical purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Deuterium Enrichment (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.