Description

Decahydro-Isoquinoline-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a rigid, saturated bicyclic structure. This compound is valued for its role as a key chiral building block in the synthesis of complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, including potential central nervous system (CNS) agents and protease inhibitors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Used as a precursor or a chiral auxiliary in stereoselective chemical transformations to introduce complex molecular architecture.
• Peptidomimetics Development: Its constrained, bicyclic carboxylic acid structure makes it suitable for designing and synthesizing peptide mimics with enhanced metabolic stability.
• Agrochemical Research: Potential application as an intermediate in the development of new, high-performance active ingredients.
• Academic & Industrial R&D: Employed in fundamental organic synthesis research and process development for scale-up to commercial manufacturing.

Basic Information

Product Name	Decahydro-Isoquinoline-1-Carboxylic Acid
CAS No.	169390-26-5
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	1,2,3,4,5,6,7,8,9,10-Decahydroisoquinoline-1-carboxylic acid; (1S,3aS,7aS)-Octahydro-1H-isoindole-1-carboxylic acid (stereoisomer); Perhydroisoquinoline-1-carboxylic acid; Decahydro-1-isoquinolinecarboxylic acid; Bicyclo[4.3.0]nonane-1-carboxylic acid derivative; DHIQ-1-COOH
EINECS	Contact for details

Quality Control

We supply Decahydro-Isoquinoline-1-Carboxylic Acid in high-purity grades suitable for demanding research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.