Description

8-Amino-3,4-dihydro-2H-isoquinolin-1-one is a versatile heterocyclic organic compound featuring a fused isoquinolinone core structure. This compound serves as a critical pharmaceutical intermediate and a valuable building block in medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Its unique scaffold makes it a key precursor for developing compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in academic and industrial labs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or biological pathways.
• Organic Synthesis Reagent: Acts as a specialized reagent or starting material for constructing complex polycyclic frameworks in advanced organic synthesis.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	8-Amino-3,4-dihydro-2H-isoquinolin-1-one
CAS No.	169045-00-5
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	8-Amino-1,2,3,4-tetrahydroisoquinolin-1-one; 8-Amino-3,4-dihydro-1(2H)-isoquinolinone; 8-Amino-1,2,3,4-tetrahydro-1-isoquinolinone; 8-Amino-1,2,3,4-tetrahydroisoquinoline-1-one; 1(2H)-Isoquinolinone, 8-amino-3,4-dihydro-; 8-Amino-1,2,3,4-tetrahydro-2H-isoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 8-Amino-3,4-dihydro-2H-isoquinolin-1-one is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.