Description

5-(Trifluoromethoxy)Isatin CAS NO 169037-23-4 is a specialized fluorinated isatin derivative, a high-value synthetic intermediate prized for its unique trifluoromethoxy substituent. This compound is critical for introducing fluorine-containing motifs into complex molecules, significantly altering their physicochemical and biological properties. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by advanced material scientists exploring functional organic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Organic Electronic Materials: Serves as a precursor for electron-deficient moieties in the development of organic semiconductors and light-emitting materials.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on incorporating fluorinated functional groups into heterocyclic scaffolds.
• Chemical Probe Development: Utilized in medicinal chemistry for creating selective probes and inhibitors to study biological pathways and enzyme functions.
• Coordination Chemistry: Acts as a ligand precursor for the synthesis of metal complexes with potential catalytic or luminescent properties.

Basic Information

Product Name	5-(Trifluoromethoxy)Isatin
CAS No.	169037-23-4
Molecular Formula	C9H4F3NO3
Molecular Weight	231.13 g/mol
Synonyms	5-(Trifluoromethoxy)-1H-indole-2,3-dione; 5-(Trifluoromethoxy)indoline-2,3-dione; 1H-Indole-2,3-dione, 5-(trifluoromethoxy)-; Isatin, 5-(trifluoromethoxy)-; 5-Trifluoromethoxyisatin
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethoxy)Isatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.