Description

(S)-6-Methoxy-2,3-Dihydro-1H-Inden-1-Amine CAS NO 168903-23-9 is a chiral amine derivative of the indane scaffold, serving as a critical building block in modern organic synthesis. This compound is valued for its defined stereochemistry and functional group versatility, enabling the construction of complex molecules with high enantiomeric purity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or resolving agent in stereoselective chemical transformations to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced, biologically active molecules for crop protection and pest management.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for catalytic asymmetric reactions.
• Chemical Reference Standard: Used as a high-purity standard in analytical method development and quality control for related pharmaceutical processes.
• Academic and Industrial R&D: A valuable tool for exploratory chemistry in academic institutions and corporate R&D laboratories focused on new chemical entities.

Basic Information

Item	Details
Product Name	(S)-6-Methoxy-2,3-Dihydro-1H-Inden-1-Amine
CAS No.	168903-23-9
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	(1S)-6-Methoxy-2,3-dihydro-1H-inden-1-amine; (S)-1-Amino-6-methoxyindane; (S)-6-Methoxyindan-1-amine; (S)-6-Methoxy-1-indanamine; (S)-6-Methoxy-2,3-dihydro-1H-inden-1-amine; (S)-6-Methoxyindanamine; (S)-6-Methoxy-1-aminoindane; (S)-1-Indanamine, 6-methoxy-
EINECS	Contact for details

Quality Control

Our production of (S)-6-Methoxy-2,3-Dihydro-1H-Inden-1-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.