Description

(1R,2R,3S,5R)-3-Amino-2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol is a high-purity, stereochemically defined chiral amine-alcohol building block of significant interest in advanced organic synthesis. Its rigid bicyclic pinane structure and functional group arrangement make it a valuable precursor for creating complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its specific stereochemistry can influence biological activity and environmental profile.
• Catalyst and Ligand Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce enantioselectivity.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and flavor ingredients that require precise stereochemical control.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties derived from its rigid core.

Basic Information

Item	Detail
Product Name	(1R,2R,3S,5R)-3-Amino-2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol
CAS No.	168286-10-0
Molecular Formula	C10H19NO
Molecular Weight	169.26 g/mol
Synonyms	(1R,2R,3S,5R)-(-)-2-Hydroxy-3-aminopinane; (1R,2R,3S,5R)-3-Amino-2-hydroxy-2,6,6-trimethylbicyclo[3.1.1]heptane; (-)-cis-Myrtanylamine; (-)-cis-Pinane-3-amino-2-ol; 3-Amino-2-hydroxy-2,6,6-trimethylbicyclo[3.1.1]heptane; Chiral Pinane Amino Alcohol; 2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol, 3-amino-, (1R,2R,3S,5R)-
EINECS	Contact for details

Quality Control

Our (1R,2R,3S,5R)-3-Amino-2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the exacting standards required for research and process development. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.