Description

Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 3-Methyl-α-Methylene-, [1S-(2-Exo,3-Exo)]- is a high-purity, stereochemically defined bicyclic compound that serves as a versatile and valuable chiral building block in advanced organic synthesis. Its unique bridged structure and functional groups make it an essential intermediate for constructing complex molecular architectures with precise spatial orientation. This product is primarily targeted at research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries who require high-quality, reliable chiral synthons.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the development of novel, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a core structure for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Building block for polymers and specialty chemicals with tailored thermal or optical properties, such as liquid crystals.
• Academic and R&D Laboratories: A critical reagent for methodological studies in organic chemistry, including Diels-Alder and other cycloaddition reactions.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex terpenoid-based aroma molecules.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 3-Methyl-α-Methylene-, [1S-(2-Exo,3-Exo)]-
CAS No.	168037-35-2
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	(1S,2R,3R,4S)-3-Methyl-2-(methylene)bicyclo[2.2.1]hept-5-ene-2-methanol; (1S)-exo,exo-3-Methyl-α-methylenebicyclo[2.2.1]hept-5-ene-2-methanol; 3-Methyl-α-methylenenorbornene-2-methanol; exo-3-Methyl-α-methylenenorborn-5-ene-2-methanol; Chiral Norbornene Derivative; Bicyclic Chiral Synthon; (1S)-(+)-3-Methyl-α-methylenenorborn-5-ene-2-methanol
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 3-Methyl-α-Methylene-, [1S-(2-Exo,3-Exo)]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.