Description

Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 3-Methyl-α-Methylene-, [1S-(2-Endo,3- is a high-purity, chiral bicyclic compound that serves as a critical advanced intermediate in sophisticated organic synthesis. Its unique and rigid molecular framework makes it an invaluable building block for constructing complex, three-dimensional architectures in pharmaceutical and specialty chemical research. This product is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and performance materials where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific stereochemical activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 3-Methyl-α-Methylene-, [1S-(2-Endo,3-
CAS No.	167901-01-1
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	3-Methyl-α-methylene-2-norbornanemethanol, (1S-endo)-; (1S,2R,3R,4S)-3-Methyl-α-methylenebicyclo[2.2.1]hept-5-ene-2-methanol; 2-Norbornene-2-methanol, 3-methyl-α-methylene-, (1S-endo)-; Chiral Bicyclic Olefin Alcohol; exo-3-Methyl-α-methylenenorborn-5-ene-2-methanol; (1S,2R,3R,4S)-3-Methyl-α-methylenenorborn-5-ene-2-methanol; Advanced Chiral Building Block NB-Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to ensure identity, purity, and enantiomeric excess meet rigorous specifications. Certificates of Analysis (COA) with full analytical data are provided for each lot, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; containers should be kept tightly sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.