Description

5-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity fluorinated indole derivative, a crucial synthetic intermediate in modern organic and medicinal chemistry. Its core value lies in its versatile indole scaffold and strategically placed fluorine atom, enabling the synthesis of complex molecules with enhanced biological activity and metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potent drug candidates, especially kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated indole structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening (HTS).
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials due to its conjugated system.

Basic Information

Product Name	5-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	167631-84-7
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	Methyl 5-Fluoro-1H-indole-2-carboxylate; 5-Fluoroindole-2-carboxylic Acid Methyl Ester; 2-Carbomethoxy-5-fluoroindole; 5-Fluoro-1H-indole-2-carboxylic acid, methyl ester; 5-Fluoro-2-indolecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.