Description

5-Fluoro-1-Methyl-1H-Indole-2-Carboxylic Acid is a high-value fluorinated indole derivative that serves as a critical building block in modern synthetic chemistry. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique structure imparts desirable biological and physicochemical properties. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced activity and stability.
• Material Science Research: Serves as a precursor for functionalized organic materials and ligands for catalytic systems.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.
• Fluorine Chemistry: An important substrate for studying fluorination effects and developing new fluorination methodologies.

Basic Information

Product Name	5-Fluoro-1-Methyl-1H-Indole-2-Carboxylic Acid
CAS No.	167631-50-7
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	5-Fluoro-1-methylindole-2-carboxylic acid; 1-Methyl-5-fluoroindole-2-carboxylic acid; 2-Carboxy-5-fluoro-1-methylindole; 5-Fluoro-1-methyl-1H-indole-2-carboxylic acid; 167631-50-7; 5-Fluoro-1-methyl-2-indolecarboxylic acid; 1-Methyl-5-fluoro-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-1-Methyl-1H-Indole-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.