Description

1-(Spiro[Indoline-3,4'-Piperidin]-1-Yl)Ethanone Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a complex building block for constructing novel heterocyclic compounds with potential biological activity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying synthetic methodologies and new chemical entities.

Basic Information

Product Name	1-(Spiro[Indoline-3,4'-Piperidin]-1-Yl)Ethanone Hcl
CAS No.	167484-19-7
Molecular Formula	C15H20N2O·HCl
Molecular Weight	280.80 g/mol
Synonyms	1-(Spiro[indoline-3,4'-piperidin]-1-yl)ethanone hydrochloride; 1'-Acetylspiro[indoline-3,4'-piperidine] hydrochloride; 1-Acetylspiro[indoline-3,4'-piperidine] HCl; Spiro[indoline-3,4'-piperidine]-1-acetone hydrochloride; 1-(1,3-Dihydrospiro[indene-2,4'-piperidin]-1-yl)ethanone hydrochloride (related); CAS 167484-19-7
EINECS	Contact for details

Quality Control

Our 1-(Spiro[Indoline-3,4'-Piperidin]-1-Yl)Ethanone Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.