Description

tert-Butyl (3-Iodopropyl)Carbamate is a versatile and high-purity organic building block, specifically a protected aminoalkyl iodide derivative. Its primary value lies in its dual functionality, serving as a key intermediate for the controlled introduction of amine and alkyl halide moieties in complex molecular synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for constructing active pharmaceutical ingredients (APIs) and advanced materials through cross-coupling and nucleophilic substitution reactions.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in medicinal chemistry for cancer, antiviral, and neurological disorder research.
• Peptide Mimetics & Linker Chemistry: Used to introduce functionalized alkyl chains or as a linker/spacer in the development of peptide-based therapeutics and bioconjugates.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Employed in the synthesis of functional monomers, specialty polymers, and dendrimers requiring specific amine or halide functionality.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Negishi, Stille) to form carbon-carbon bonds.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group provides orthogonal protection for amines in multi-step synthetic sequences.

Basic Information

Product Name	tert-Butyl (3-Iodopropyl)Carbamate
CAS No.	167479-01-8
Molecular Formula	C8H16INO2
Molecular Weight	285.12 g/mol
Synonyms	N-Boc-3-iodopropylamine; 3-Iodopropyl tert-butylcarbamate; tert-Butyl N-(3-iodopropyl)carbamate; 1-(tert-Butoxycarbonylamino)-3-iodopropane; Boc-3-iodopropylamine; N-(tert-Butoxycarbonyl)-3-iodopropylamine; 3-Iodo-1-propylamine, N-Boc-protected; Boc-NH-(CH2)3-I
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-Iodopropyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.