Description

1-(2-Amino-4-(Trifluoromethyl)Thiazol-5-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazole ring and trifluoromethyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially in antiviral, antibacterial, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the thiazole moiety.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialized organic materials and ligands for catalytic systems.

Basic Information

Product Name	1-(2-Amino-4-(Trifluoromethyl)Thiazol-5-Yl)Ethanone
CAS No.	167405-28-9
Molecular Formula	C6H5F3N2OS
Molecular Weight	210.18 g/mol
Synonyms	5-Acetyl-2-amino-4-(trifluoromethyl)thiazole; 2-Amino-4-(trifluoromethyl)-5-acetylthiazole; 5-Acetyl-4-(trifluoromethyl)-2-thiazolamine; 1-[2-Amino-4-(trifluoromethyl)-1,3-thiazol-5-yl]ethanone; Ethanone, 1-[2-amino-4-(trifluoromethyl)-5-thiazolyl]-; 167405-28-9
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-4-(Trifluoromethyl)Thiazol-5-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.