Description

4-Bromo-2-Formylthiazole CAS NO 167366-05-4 is a versatile and highly functionalized heterocyclic building block, specifically a brominated thiazole aldehyde. This compound is valued for its dual reactive sites, which enable its use as a key intermediate in the synthesis of complex molecules across advanced research and industrial chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require precise and reliable building blocks for constructing novel thiazole-based compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle in bioconjugation chemistry and for the development of molecular probes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Ligand Synthesis: Used to prepare novel nitrogen-sulfur (N,S) donor ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromo-2-Formylthiazole
CAS No.	167366-05-4
Molecular Formula	C4H2BrNOS
Molecular Weight	192.03 g/mol
Synonyms	4-Bromo-1,3-thiazole-2-carboxaldehyde; 4-Bromothiazole-2-carbaldehyde; 2-Formyl-4-bromothiazole; 4-Bromo-2-thiazolecarboxaldehyde; 4-Bromothiazole-2-carboxaldehyde; 4-Bromo-2-thiophenecarboxaldehyde (incorrect but common misnomer); 4-Bromo-2-thiazolylaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Formylthiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality ensures a reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.