Description

1-n-Boc-4-(2-Thienyl)Piperidine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core functionalized with a thienyl group and a protected amine. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other bioactive molecules. Its structural complexity and defined stereochemistry make it an essential component for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting neurological disorders and various enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse piperidine-based compound libraries.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research-scale synthesis of complex molecules during early-stage API process development.
• Bioconjugation & Probe Synthesis: Can be utilized in the development of chemical probes for biological target identification and validation.

Basic Information

Product Name	1-n-Boc-4-(2-Thienyl)Piperidine-4-Carbonitrile
CAS No.	167263-68-5
Molecular Formula	C15H20N2O2S
Molecular Weight	292.40 g/mol
Synonyms	1-Boc-4-(2-Thienyl)-4-cyanopiperidine; tert-Butyl 4-cyano-4-(thiophen-2-yl)piperidine-1-carboxylate; 4-Cyano-4-(2-thienyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(2-thienyl)-4-cyanopiperidine; 4-(Thiophen-2-yl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(2-thienyl)piperidine-4-carbonitrile; 4-Cyano-4-(2-thienyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-n-Boc-4-(2-Thienyl)Piperidine-4-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is accompanied by a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development applications, with specifications tailored to support cGMP-compliant workflows where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.