Description

4-Bromo-2,5-Dichlorothiophene-3-Sulfonyl Chloride is a high-value, multi-functional sulfonyl chloride derivative used as a key synthetic intermediate. Its reactive sulfonyl chloride and halogenated thiophene core make it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors where the thiophene-sulfonamide scaffold is pharmacologically active.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Functional Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, dyes, and electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and constructing complex molecular libraries for screening.
• Sulfonamide & Sulfonate Derivative Production: The reactive sulfonyl chloride group enables efficient synthesis of a wide range of sulfonamides, sulfonate esters, and other sulfonyl-containing compounds.

Basic Information

Product Name	4-Bromo-2,5-Dichlorothiophene-3-Sulfonyl Chloride
CAS No.	166964-36-9
Molecular Formula	C4BrCl2NO2S2
Molecular Weight	335.89 g/mol
Synonyms	4-Bromo-2,5-dichlorothiophene-3-sulfonyl chloride; 3-Thiophenesulfonyl chloride, 4-bromo-2,5-dichloro-; 2,5-Dichloro-4-bromothiophene-3-sulfonyl chloride; 4-Bromo-2,5-dichloro-3-thiophenesulfonyl chloride; 166964-36-9; 4-Bromo-2,5-dichlorothiophene-3-SO2Cl
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,5-Dichlorothiophene-3-Sulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.