Description

Benzenemethanol, -α-,2,4-Trimethyl-, (-α-R)- (9Ci) is a chiral aromatic alcohol derivative, characterized by its specific stereochemistry and trimethyl-substituted benzene ring. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, where its defined stereocenter is critical for producing enantiomerically pure products. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for applications such as asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the asymmetric synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development and production of enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring high stereochemical purity.
• Material Science Research: Investigated as a monomer or modifying agent for creating novel polymers with specific chiral properties.

Basic Information

Product Name	Benzenemethanol, -α-,2,4-Trimethyl-, (-α-R)- (9Ci)
CAS No.	166940-44-9
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(R)-α,2,4-Trimethylbenzyl Alcohol; (R)-1-(2,4-Dimethylphenyl)ethanol; (R)-2,4-Dimethyl-α-methylbenzyl Alcohol; (-)-(R)-α,2,4-Trimethylbenzenemethanol; Benzenemethanol, α,2,4-trimethyl-, (αR)-; (R)-1-(2,4-Dimethylphenyl)ethan-1-ol; (R)-HMPB-OH (context-dependent); Chiral Trimethylbenzyl Alcohol
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, -α-,2,4-Trimethyl-, (-α-R)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure high enantiomeric excess (ee) and chemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its property of being easily oxidized, prolonged exposure to air should be avoided. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.