Description

2-(Bromomethyl)-5-(Phthalimidomethyl)Thiophene is a high-purity, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is valued for its dual reactive sites, enabling its use as a key intermediate in the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts.
• Fluorescent Probe Synthesis: Acts as a core structure for synthesizing thiophene-based fluorescent dyes and biological imaging agents.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP guidelines.

Basic Information

Product Name	2-(Bromomethyl)-5-(Phthalimidomethyl)Thiophene
CAS No.	166888-26-2
Molecular Formula	C15H12BrNO2S
Molecular Weight	350.23 g/mol
Synonyms	5-(Phthalimidomethyl)-2-(bromomethyl)thiophene; 2-Bromomethyl-5-phthalimidomethylthiophene; Thiophene, 2-(bromomethyl)-5-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-; 1,3-Dihydro-2-[5-[(2-bromoethyl)thien-2-yl]methyl]-1,3-dioxoisoindole; 2-(Bromomethyl)-5-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]thiophene
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-5-(Phthalimidomethyl)Thiophene is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of research and pre-clinical development. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and mass spectrometry data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.