Description

5-(3-Methylphenyl)-2-Thiophenecarboxylic Acid is a high-purity organic building block featuring a thiophene core substituted with a carboxylic acid group and a meta-methylphenyl moiety. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the thiophene scaffold for enhanced biological activity.
• Material Science Research: Serves as a precursor for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene structure.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for coordination to metal centers, making it useful in designing novel catalysts and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value heterocyclic carboxylic acids.

Basic Information

Item	Details
Product Name	5-(3-Methylphenyl)-2-Thiophenecarboxylic Acid
CAS No.	166591-62-4
Molecular Formula	C12H10O2S
Molecular Weight	218.27 g/mol
Synonyms	5-(3-Methylphenyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-(3-methylphenyl)-; 5-(m-Tolyl)thiophene-2-carboxylic acid; 5-(3-Methylphenyl)-2-thiophenecarboxylic acid; 5-(3-Methylphenyl)thiophene-2-carboxylate; 166591-62-4; 5-(3-Methylphenyl)-2-thiophenecarboxylic acid (CAS 166591-62-4)
EINECS	Contact for details

Quality Control

Our production of 5-(3-Methylphenyl)-2-Thiophenecarboxylic Acid adheres to stringent quality management protocols. Every batch is analytically verified using advanced techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all critical parameters is provided with each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.