Description

1,2,3,4-Tetrahydroisoquinoline-6-Carbonitrile is a versatile heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its core structure makes it a valuable precursor for the development of complex pharmacologically active molecules. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of central nervous system (CNS) active drugs, alkaloid derivatives, and other bioactive molecules.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the tetrahydroisoquinoline scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials due to its electron-withdrawing nitrile group and aromatic system.
• Academic and R&D Laboratories: A fundamental building block for methodological studies in organic chemistry, including cyclization and functional group transformation reactions.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline-6-Carbonitrile
CAS No.	166398-34-1
Molecular Formula	C10H10N2
Molecular Weight	158.20 g/mol
Synonyms	6-Cyano-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-cyanoisoquinoline; THIQ-6-CN; 6-CN-THIQ; Isoquinoline-6-carbonitrile, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydroisoquinolin-6-yl cyanide
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.