Description

4-(3,4-Dihydroisoquinolin-2(1H)-Yl)Cyclohexanone is a versatile organic building block featuring a fused dihydroisoquinoline and cyclohexanone scaffold. This compound matters as a key synthetic intermediate in the development of complex, biologically active molecules, offering a unique structural motif for medicinal chemistry research. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting various receptors and enzymes.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Alkaloid Analog Synthesis: Used to construct complex heterocyclic systems and analogs of natural isoquinoline alkaloids.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for biological pathway investigation.
• Fine Chemical Synthesis: Utilized in custom and contract synthesis for producing high-value, specialized organic compounds.
• Academic Research: Applied in university and institutional labs for methodological development and novel organic synthesis.

Basic Information

Product Name	4-(3,4-Dihydroisoquinolin-2(1H)-Yl)Cyclohexanone
CAS No.	166398-23-8
Molecular Formula	C15H19NO
Molecular Weight	229.32 g/mol
Synonyms	4-(1,2,3,4-Tetrahydroisoquinolin-2-yl)cyclohexanone; 2-(4-Oxocyclohexyl)-1,2,3,4-tetrahydroisoquinoline; Cyclohexanone, 4-(1,2,3,4-tetrahydro-2-isoquinolinyl)-; 4-(3,4-Dihydro-2(1H)-isoquinolinyl)cyclohexanone; 4-(1,2,3,4-Tetrahydroisoquinolin-2-yl)cyclohexan-1-one
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dihydroisoquinolin-2(1H)-Yl)Cyclohexanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.