Description

1-Bromo-4-(Methoxymethyl)-2-Methylbenzene is a versatile brominated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a methoxymethyl ether group, makes it a valuable precursor for constructing complex molecules through cross-coupling and functional group transformations. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in constructing complex aromatic cores for small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its halogen and ether functionalities are leveraged for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for specialty polymers.
• Cross-Coupling Reactions: Acts as a reliable electrophilic partner in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Fine Chemical Production: Utilized in custom and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	1-Bromo-4-(Methoxymethyl)-2-Methylbenzene
CAS No.	166386-61-4
Molecular Formula	C9H11BrO
Molecular Weight	215.09 g/mol
Synonyms	4-Bromo-3-methylbenzyl methyl ether; 2-Methyl-4-(methoxymethyl)bromobenzene; 1-Bromo-4-methoxymethyl-2-methylbenzene; p-Bromo-m-methylbenzyl methyl ether; (4-Bromo-3-methylphenyl)methanol methyl ether; Benzene, 1-bromo-4-(methoxymethyl)-2-methyl-; Bromo(methoxymethyl)methylbenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Methoxymethyl)-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.