Description

1-Boc-5-Aminoindole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a stable, reactive intermediate for constructing complex nitrogen-containing heterocycles. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of novel organic electronic materials and functional dyes.
• Academic & R&D: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Facilitates the incorporation of indole-based structures into peptide analogs to enhance stability and bioactivity.

Basic Information

Product Name	1-Boc-5-Aminoindole
CAS No.	166104-20-7
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	5-Amino-1-[(tert-butoxy)carbonyl]indole; 1-(tert-Butoxycarbonyl)-5-aminoindole; tert-Butyl 5-amino-1H-indole-1-carboxylate; 5-Amino-1H-indole-1-carboxylic acid, 1,1-dimethylethyl ester; 1-Boc-5-aminoindole; Boc-5-AI; 5-Aminoindole-1-carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Aminoindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.