Description

5-Thiazolepropanal, 4-Methyl- is a specialized heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique thiazole core with a reactive propanal side chain makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials for electronic applications.
• Flavor & Fragrance Chemistry: Acts as an intermediate for creating complex sulfur-containing aroma compounds in high-value applications.
• Academic & Contract Research: A valuable reagent for methodological studies and the exploration of new heterocyclic chemistry in university and CRO laboratories.

Basic Information

Product Name	5-Thiazolepropanal, 4-Methyl-
CAS No.	165685-93-8
Molecular Formula	C7H9NOS
Molecular Weight	155.22 g/mol
Synonyms	4-Methyl-5-thiazolepropanal; 4-Methyl-5-(2-oxoethyl)thiazole; 3-(4-Methyl-1,3-thiazol-5-yl)propanal; 5-Thiazolepropanal, 4-methyl-; 4-Methylthiazole-5-propanal; 4-Methyl-5-thiazoleethanol aldehyde; 2-(4-Methylthiazol-5-yl)acetaldehyde (tautomeric form); 165685-93-8
EINECS	Contact for details

Quality Control

Every batch of 5-Thiazolepropanal, 4-Methyl- is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (typically by HPLC), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical development, and we can tailor specifications to meet the exacting requirements of your project.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the container to reach ambient temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.