Description

1-Ethyl-2,2,4,4,4-Pentakis(Dimethylamino)-2Lambda5,4Lambda5-Catenadi(Phosphazene) is a highly specialized, nitrogen-rich organophosphorus compound belonging to the phosphazene superbase family. This compound matters for its exceptional basicity and non-nucleophilic character, making it a powerful catalyst and reagent in demanding synthetic transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications requiring strong, non-ionic bases.

Application

• Pharmaceutical Synthesis: As a potent, non-nucleophilic base for deprotonation reactions, particularly in the synthesis of sensitive or complex drug intermediates where traditional bases like LDA or n-BuLi are unsuitable.
• Polymer Chemistry: Catalyst for the ring-opening polymerization (ROP) of cyclic esters (e.g., lactides, lactones) to produce biodegradable polyesters like PLA and PCL with controlled molecular weights.
• Advanced Material Production: Used in the synthesis of phosphazene-based polymers and hybrid materials with unique thermal stability and flame-retardant properties.
• Organic Methodology Development: A key reagent in academic and industrial R&D for developing new catalytic cycles and promoting challenging C-C and C-N bond-forming reactions under mild conditions.
• Fine Chemical Manufacturing: Facilitates high-yield, selective reactions in the production of agrochemicals, dyes, and specialty chemicals where side reactions must be minimized.

Basic Information

Product Name	1-Ethyl-2,2,4,4,4-Pentakis(Dimethylamino)-2Lambda5,4Lambda5-Catenadi(Phosphazene)
CAS No.	165535-45-5
Molecular Formula	C14H42N11P2
Molecular Weight	426.52 g/mol
Synonyms	Phosphazene Base P4-Et; t-Bu-P4; Ethyltris(dimethylamino)phosphonium tris(dimethylamino)phosphinimine; 1-Ethyl-2,2,4,4,4-pentakis(dimethylamino)-2λ5,4λ5-catenadi(phosphazene); Verkade's Superbase (P4-Et); P4-Ethyl Superbase; Ethyl-Substituted Phosphazene Base; BEMP analogue (ethyl variant)
EINECS	Contact for details

Quality Control

Every batch of our 1-Ethyl-2,2,4,4,4-Pentakis(Dimethylamino)-2Lambda5,4Lambda5-Catenadi(Phosphazene) is synthesized and handled under strict quality protocols to ensure consistency and performance. We provide comprehensive analytical data including NMR (1H, 13C, 31P) and HPLC purity analysis to verify chemical identity and assay. Certificates of Analysis (COA) detailing all specifications are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.