Description

Doramectin Monosaccharide is a key monosaccharide derivative of the potent macrocyclic lactone anthelmintic, doramectin. This high-purity intermediate is critical for the synthesis and formulation of advanced veterinary pharmaceuticals. It is primarily utilized by manufacturers in the animal health industry for producing effective parasitic control solutions. Its defined chemical structure ensures consistent performance in end-use applications.

Application

• Primary intermediate in the synthesis of Doramectin and related end-use pharmaceutical formulations.
• Active pharmaceutical ingredient (API) for injectable or pour-on veterinary parasiticides targeting endo- and ectoparasites.
• Manufacturing of broad-spectrum anthelmintics for livestock, including cattle, sheep, and swine.
• Research and development of novel macrocyclic lactone derivatives with enhanced efficacy or safety profiles.
• Production of medicated feed additives or premixes for herd-level parasite management programs.
• Quality control and analytical reference standard for HPLC assay development in pharmaceutical QC laboratories.

Basic Information

Product Name	Doramectin Monosaccharide
CAS No.	165108-44-1
Molecular Formula	C₃₃H₅₀O₉
Molecular Weight	606.75 g/mol
Synonyms	25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl) Avermectin A1a Monosaccharide; 5-O-Desmethyl-25-de(1-methylpropyl)-25-cyclohexyl Avermectin A1a Monosaccharide; Doramectin Aglycone Monosaccharide; Doramectin Derivative; (2aE,4E,8E)-5-[(1R,2S,6S,7R,11S,13S,15R,17R,20S,21S)-13-[(2S,4S,5S)-5-Cyclohexyl-4-hydroxy-5-methyltetrahydro-2H-pyran-2-yl]-17-ethyl-1,2,6,7,15,20,21-heptahydroxy-11,21-dimethyldocosa-2a,4,8,19-tetraen-10-yliden]-2,6-dihydroxy-3-methylhept-4-enoic Acid
EINECS	Contact for details

Quality Control

Our Doramectin Monosaccharide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.