Description

22,23-Didehydro Selamectin is a key intermediate and derivative of the macrocyclic lactone selamectin, a well-known active pharmaceutical ingredient. This compound is of significant interest for research and development within the pharmaceutical and veterinary medicine sectors, particularly for the synthesis of novel antiparasitic agents. It is primarily utilized by manufacturers and R&D laboratories focused on developing advanced endectocide treatments for animal health.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of selamectin and related macrocyclic lactone compounds.
• Veterinary Drug R&D: Used in research programs aimed at developing new or improved broad-spectrum antiparasitic formulations for companion animals and livestock.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing selamectin-based products.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the behavior of selamectin in biological systems.
• Process Chemistry: Utilized in scale-up and optimization of manufacturing processes for selamectin active pharmaceutical ingredient (API).
• Academic Research: A valuable compound for university and institutional studies in medicinal chemistry and parasitology.

Basic Information

Product Name	22,23-Didehydro Selamectin
CAS No.	165108-09-8
Molecular Formula	C43H63NO11
Molecular Weight	769.97 g/mol
Synonyms	Selamectin Impurity; 22,23-Didehydroselamectin; (5Z,25S)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-didehydro-5-(hydroxyimino)avermectin A1a; Selamectin Related Compound; 22,23-Dehydro Selamectin; Selamectin Derivative; 165108-09-8
EINECS	Contact for details

Quality Control

Our 22,23-Didehydro Selamectin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is light-sensitive (store away from light) and should be handled under inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.