Description

Avermectin A1A, 25-Cyclohexyl-4-o-De(2,6-Dideoxy-3-o-Methyl-.Alpha.-L-Arabino-Hexopyranosyl)-5-Demethoxy-25-De(1-Methylpropyl)-22,23-Dihydro-5-(Hydroxyimino)- is a structurally complex, semi-synthetic derivative of the naturally occurring avermectin family, known for its potent biological activity. This compound is engineered for high specificity and serves as a critical advanced intermediate in the synthesis of next-generation parasiticides and agrochemicals. It is essential for R&D and manufacturing sectors focused on developing novel solutions in veterinary pharmaceuticals and crop protection.

Application

• Key Intermediate in Agrochemical Synthesis: Used in the research and production of novel, high-efficacy insecticides and miticides for crop protection.
• Veterinary Pharmaceutical Development: Serves as a crucial building block for creating new endectocide formulations targeting parasites in livestock and companion animals.
• Biochemical Research: Employed in academic and industrial laboratories to study structure-activity relationships (SAR) within the macrocyclic lactone class.
• Process Chemistry & Scale-Up: Utilized by chemical manufacturers for process optimization and the pilot-scale synthesis of specialized active ingredients.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory testing in related product manufacturing.

Basic Information

Product Name	Avermectin A1A, 25-Cyclohexyl-4-o-De(2,6-Dideoxy-3-o-Methyl-.Alpha.-L-Arabino-Hexopyranosyl)-5-Demethoxy-25-De(1-Methylpropyl)-22,23-Dihydro-5-(Hydroxyimino)-
CAS No.	165108-07-6
Molecular Formula	C47H71NO13
Molecular Weight	858.1 g/mol
Synonyms	5-(Hydroxyimino)-avermectin A1a aglycone; 5-Oxime Avermectin A1a Derivative; 25-Cyclohexyl-5-(hydroxyimino)avermectin A1a; 4"-Deoxy-4"-epi-methylamino-avermectin B1a 5-oxime; Avermectin A1A Oxime Derivative; 5-(Hydroxyimino)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydroavermectin A1a; 25-Cyclohexyl Avermectin A1a 5-Oxime
EINECS	Contact for details

Quality Control

Our Avermectin A1A derivative is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.