Description

3-Thiophenecarboxylicacid,4-Aminotetrahydro-,cis-(9Ci) is a specialized heterocyclic building block featuring a cis-configured, saturated thiophene ring with both carboxylic acid and amino functional groups. This unique molecular architecture makes it a valuable intermediate for the synthesis of complex pharmacologically active compounds and advanced materials. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas like enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to the thiophene moiety.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	3-Thiophenecarboxylicacid,4-Aminotetrahydro-,cis-(9Ci)
CAS No.	164916-45-4
Molecular Formula	C6H9NO2S
Molecular Weight	159.21 g/mol
Synonyms	cis-4-Aminotetrahydro-3-thiophenecarboxylic acid; 4-Amino-3-thiophenecarboxylic acid, tetrahydro-, cis-; 3-Thiophenecarboxylic acid, 4-aminohexahydro-, cis-; cis-4-Amino-3-carboxythiolane; (3R,4S)-4-Amino-3-thiophenecarboxylic acid (if stereochemistry is defined); 4-Aminotetrahydrothiophene-3-carboxylic acid, cis-; Tetrahydro-4-amino-3-thiophenecarboxylic acid, cis-; 3-Carboxy-4-aminothiolane, cis-
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxylicacid,4-Aminotetrahydro-,cis-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.