Description

6-Amino-2-n-Boc-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, protected heterocyclic amine building block of significant importance in modern synthetic organic chemistry. This compound is valued for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of tetrahydroisoquinoline-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate the rigid, nitrogen-containing tetrahydroisoquinoline scaffold into larger molecules to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators that utilize the isoquinoline structure.
• Ligand & Catalyst Development: Employed in the creation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	6-Amino-2-n-Boc-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	164148-92-9
Molecular Formula	C₁₄H₂₀N₂O₂
Molecular Weight	248.32 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-1,2,3,4-tetrahydroisoquinolin-6-amine; 6-Amino-2-[(tert-butoxycarbonyl)amino]-1,2,3,4-tetrahydroisoquinoline; 2-N-Boc-amino-6-amino-1,2,3,4-tetrahydroisoquinoline; 2-(tert-Butoxycarbonylamino)-1,2,3,4-tetrahydro-6-isoquinolinamine; 6-Amino-2-Boc-1,2,3,4-tetrahydroisoquinoline; Boc-6-Amino-THIQ; 6-Amino-2-Boc-THIQ
EINECS	Contact for details

Quality Control

Our 6-Amino-2-n-Boc-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.