Description

3-Iodo-1-Thiophen-2-Yl-Propan-1-Ol is a valuable iodinated heterocyclic building block, specifically a thiophene derivative with a functionalized propanol side chain. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its unique molecular architecture, which allows for selective chemical modifications. It serves as a critical intermediate for medicinal chemists and process development scientists working in the fields of drug discovery and agrochemical development. The reactive iodine and alcohol functionalities make it a versatile precursor for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the creation of new pesticide and herbicide candidates, leveraging the thiophene moiety for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of conductive polymers and advanced organic electronic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.

Basic Information

Product Name	3-Iodo-1-Thiophen-2-Yl-Propan-1-Ol
CAS No.	164071-58-3
Molecular Formula	C7H9IOS
Molecular Weight	268.11 g/mol
Synonyms	3-Iodo-1-(2-thienyl)-1-propanol; 1-(Thiophen-2-yl)-3-iodopropan-1-ol; 2-Thienyl-3-iodo-1-propanol; 3-Iodopropyl 2-thienyl ketone, reduced; (3-Iodopropyl)(thiophen-2-yl)methanol; 164071-58-3; 3-Iodo-1-(2-thienyl)propan-1-ol
EINECS	Contact for details

Quality Control

Our 3-Iodo-1-Thiophen-2-Yl-Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.