Description

Monensin Decyl Ester is a semi-synthetic derivative of the polyether ionophore antibiotic Monensin, where the carboxylic acid group is esterified with decyl alcohol. This chemical modification enhances its lipophilicity and alters its biological activity profile, making it a valuable intermediate for research and development. It is primarily utilized by pharmaceutical and life science researchers investigating novel antimicrobial agents, veterinary products, and as a biochemical tool for studying ion transport mechanisms.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel antimicrobial and antiparasitic drug candidates.
• Veterinary Research: Investigated for potential use in developing next-generation coccidiostats and growth promoters for livestock.
• Biochemical Research: Used as a research-grade ionophore to study sodium and potassium ion transport across biological membranes in cell biology experiments.
• Antimicrobial Studies: Serves as a reference compound or modified analog in structure-activity relationship (SAR) studies against Gram-positive bacteria and protozoa.
• Specialty Chemical Synthesis: Employed in organic synthesis to create more complex, targeted derivatives for specific biological applications.

Basic Information

Product Name	Monensin Decyl Ester
CAS No.	164066-23-3
Molecular Formula	C43H76O11
Molecular Weight	769.06 g/mol
Synonyms	Monensin Decyl Ester; Decyl Monensin; Monensin Decyl; Monensin n-Decyl Ester; 2-[(2R,3S,4R,5R,6S)-5-[(2S,3R,4S,6R)-4,6-Dihydroxy-3-methyl-6-[(2R,3R,5R,6S)-3-methyl-5-[(2R,3R,5S,6R)-5-methyl-6-[(2R,5S,6R)-5-methyl-5-(1-oxodecoxy)-6-(2-methylbutyl)tetrahydro-2H-pyran-2-yl]tetrahydro-2H-pyran-2-yl]tetrahydro-2H-pyran-2-yl]-2-propyltetrahydro-2H-pyran-2-yl]-3,4,5-trihydroxy-6-methyloxan-2-yl]-5-ethyl-2,5-dihydrofuran-3-yl]acetic acid; Antibiotic X 14994 Decyl Ester
EINECS	Contact for details

Quality Control

Our Monensin Decyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.