Description

Methyl Bromoacetate-2,2-D2 is a deuterated isotopologue of methyl bromoacetate, where two hydrogen atoms at the 2-position are replaced with deuterium. This deuteration makes it a critical building block for introducing stable isotopic labels into target molecules, enabling advanced research in mechanistic studies and metabolic pathway analysis. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of deuterated compounds.

Application

• Deuterated Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) with deuterium incorporation for improved metabolic stability and pharmacokinetic profiles (deuterated drugs).
• Mechanistic Probe in Organic Chemistry: Used as a labeled reagent in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms and pathways.
• Agrochemical Research: Production of deuterated analogs of pesticides and herbicides for environmental fate and metabolism studies.
• NMR Spectroscopy & Mass Spectrometry: Serves as an internal standard or a precursor for labeled standards in analytical chemistry, enhancing detection accuracy.
• Material Science Precursor: Used in the synthesis of specialty polymers and organic electronic materials where isotopic purity can influence physical properties.
• Biochemical Tracer: Facilitates the tracking of metabolic pathways in biological systems when incorporated into probe molecules.

Basic Information

Product Name	Methyl Bromoacetate-2,2-D2
CAS No.	163886-16-6
Molecular Formula	C3H3D2BrO2
Molecular Weight	154.97 g/mol (approx.)
Synonyms	Methyl 2-bromoacetate-2,2-d2; Bromoacetic-2,2-d2 acid methyl ester; Deuterated Methyl Bromoacetate; Methyl (2,2-Dideuterio-2-bromoacetate); 2-Bromoacetic-2,2-d2 Acid Methyl Ester; Methyl α-bromoacetate-2,2-d2; Methyl Bromo(d2)acetate; Methyl 2-bromo-2,2-dideuteroacetate
EINECS	Contact for details

Quality Control

Our Methyl Bromoacetate-2,2-D2 is produced under stringent conditions to ensure high isotopic and chemical purity, meeting the exacting requirements of research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by GC or HPLC), isotopic enrichment (by 1H NMR or MS), and identity confirmation. We adhere to cGMP principles where applicable, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isotopic Enrichment (D)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.