Description

1-Bromopropane-1,1,2,2-D4 is a deuterated isotopologue of 1-bromopropane, where four hydrogen atoms are replaced with deuterium, a stable hydrogen isotope. This deuteration is critical for applications requiring non-radioactive isotopic labeling, such as in NMR spectroscopy and mass spectrometry, where it serves as an internal standard or a tracer. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled building blocks for mechanistic studies, metabolic research, and the synthesis of deuterated compounds.

Application

• NMR Spectroscopy Internal Standard: Used as a chemical shift reference or quantification standard in nuclear magnetic resonance (NMR) analysis due to its distinct spectral signature.
• Mass Spectrometry Tracer: Employed in GC-MS or LC-MS as a stable isotope-labeled internal standard for accurate quantification and metabolic pathway tracing.
• Deuterated Pharmaceutical Synthesis: Serves as a key deuterium-labeled synthon in the research and development of deuterated drug candidates, which can offer improved metabolic stability.
• Mechanistic Reaction Studies: Utilized in kinetic isotope effect (KIE) studies to investigate reaction mechanisms in organic chemistry and catalysis.
• Agrochemical Research: Applied in the synthesis of labeled compounds for studying the environmental fate, metabolism, and residue analysis of pesticides.
• Advanced Materials Development: Used in the synthesis of deuterated polymers or organic electronic materials to study structure-property relationships.

Basic Information

Product Name	1-Bromopropane-1,1,2,2-D4
CAS No.	163400-21-3
Molecular Formula	C3D4H3Br
Molecular Weight	127.00 g/mol (approx.)
Synonyms	1-Bromopropane-d4; Propane-1,1,2,2-d4, 1-bromo-; 1-Bromo-1,1,2,2-tetradeuteriopropane; n-Propyl-d4 bromide; Deuterated 1-bromopropane; [1,1,2,2-2H4]Propyl bromide; Bromopropane-d4
EINECS	Contact for details

Quality Control

Our 1-Bromopropane-1,1,2,2-D4 is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR and GC-MS, to confirm isotopic purity (D-enrichment) and chemical purity. A detailed Certificate of Analysis (COA) is provided, reporting key parameters such as assay, isotopic enrichment level, and solvent residues. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are securely sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Isotopic Purity (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.