Description

5-(4-Trifluoromethyl-Phenyl)-1H-Indole is a high-value, multi-functional indole derivative characterized by its trifluoromethylphenyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging the biological activity of the indole core and the metabolic stability imparted by the trifluoromethyl group.
• Material Science: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated structure.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic systems via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Biochemical Research: Used as a probe or inhibitor in studying enzyme mechanisms and protein interactions in life science research.

Basic Information

Product Name	5-(4-Trifluoromethyl-Phenyl)-1H-Indole
CAS No.	163105-69-9
Molecular Formula	C15H10F3N
Molecular Weight	261.24 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]-1H-indole; 1H-Indole, 5-[4-(trifluoromethyl)phenyl]-; 5-(4-Trifluoromethylphenyl)indole; 5-(p-Trifluoromethylphenyl)indole; 5-(α,α,α-Trifluoro-p-tolyl)indole; 163105-69-9; 5-(4-Trifluoromethylphenyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 5-(4-Trifluoromethyl-Phenyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.