Description

S-3-Phenyl-2-[n-(Trifluoroacetyl)Pyrrolidin-2-Yl]Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-pyrrolidine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of complex bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its privileged scaffold.
• Protease Inhibitor Development: Serves as a core structure in the research of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and methodology development.

Basic Information

Product Name	S-3-Phenyl-2-[n-(Trifluoroacetyl)Pyrrolidin-2-Yl]Indole
CAS No.	163064-67-3
Molecular Formula	C20H17F3N2O
Molecular Weight	358.36 g/mol
Synonyms	(S)-3-Phenyl-2-(1-(trifluoroacetyl)pyrrolidin-2-yl)-1H-indole; 1H-Indole, 3-phenyl-2-[1-(trifluoroacetyl)-2-pyrrolidinyl]-, (2S)-; (S)-2-(1-(Trifluoroacetyl)pyrrolidin-2-yl)-3-phenyl-1H-indole; S-2-(N-Trifluoroacetylpyrrolidin-2-yl)-3-phenylindole; (S)-3-Phenyl-2-(N-trifluoroacetylpyrrolidin-2-yl)indole; 163064-67-3; S-TFA-Phenylindole Pyrrolidine
EINECS	Contact for details

Quality Control

Our S-3-Phenyl-2-[n-(Trifluoroacetyl)Pyrrolidin-2-Yl]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.