Description

(1S,2S)-(+)-trans-1-Amino-2-Indanol is a high-purity chiral amino alcohol building block of significant importance in asymmetric synthesis. Its rigid trans-1,2-diamino backbone makes it an indispensable chiral ligand and catalyst precursor for a wide range of stereoselective transformations. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Chiral Ligand in Asymmetric Catalysis: A key component for ligands used in asymmetric hydrogenation, epoxidation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: Critical building block in the synthesis of protease inhibitors (e.g., HIV-1 protease inhibitors) and other chiral drug molecules.
• Resolution Agent: Used for the chiral resolution of racemic mixtures of acids and other compounds.
• Organocatalyst Precursor: Serves as a precursor for developing novel organocatalysts for green chemistry applications.
• Research & Development: A valuable tool for academic and industrial R&D in medicinal chemistry and synthetic methodology.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(1S,2S)-(+)-trans-1-Amino-2-Indanol
CAS No.	163061-74-3
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(1S,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol; (1S,2S)-1-Aminoindan-2-ol; (+)-trans-1-Amino-2-indanol; (1S,2S)-(+)-1,2-Aminoindanol; (1S,2S)-2-Amino-1-indanol; trans-(1S,2S)-1-Amino-2-indanol; (1S,2S)-1-Amino-2-hydroxyindane; AIDN
EINECS	Contact for details

Quality Control

We supply (1S,2S)-(+)-trans-1-Amino-2-Indanol in high-purity grades suitable for demanding applications in pharmaceutical research and catalysis. Our products undergo rigorous quality testing, including chiral purity verification by HPLC, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.