Description

2-[(2,2,2-Trifluoroethyl)Thio]-Pyridine is a specialized organosulfur and organofluorine compound, serving as a high-value building block in advanced chemical synthesis. Its molecular architecture, featuring a pyridine ring linked to a trifluoroethylthio group, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the trifluoroethylthio moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with unique electronic or surface properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and biological pathways due to its potential as a bioisostere.

Basic Information

Product Name	2-[(2,2,2-Trifluoroethyl)Thio]-Pyridine
CAS No.	162965-54-0
Molecular Formula	C7H6F3NS
Molecular Weight	193.19 g/mol
Synonyms	2-[(2,2,2-Trifluoroethyl)sulfanyl]pyridine; Pyridine, 2-[(2,2,2-trifluoroethyl)thio]-; 2-(Trifluoroethylthio)pyridine; 2-Pyridyl 2,2,2-trifluoroethyl sulfide; 2-(2,2,2-Trifluoroethylsulfanyl)pyridine; 2-(Trifluoroethylmercapto)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-[(2,2,2-Trifluoroethyl)Thio]-Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.