Description

5-Bromo-4-Methoxythiophene-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique thiophene scaffold enables the creation of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and advanced organic electronic materials due to its electron-rich thiophene core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and functional pigments.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	5-Bromo-4-Methoxythiophene-3-Carboxylic Acid
CAS No.	162848-23-9
Molecular Formula	C7H5BrO3S
Molecular Weight	249.08 g/mol
Synonyms	5-Bromo-4-methoxy-3-thiophenecarboxylic acid; 3-Thiophenecarboxylic acid, 5-bromo-4-methoxy-; 4-Methoxy-5-bromothiophene-3-carboxylic acid; 5-Bromo-4-methoxythiophene-3-carboxylate; 162848-23-9; 5-Br-4-MeO-thiophene-3-COOH
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Methoxythiophene-3-Carboxylic Acid is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.