Description

Bicyclo[2.2.1]Heptan-2-Ol, 5,6-Difluoro-, Acetate, (2-Endo,5-Exo,6-Exo)- (9Ci) is a high-purity, stereochemically defined fluorinated bicyclic compound, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in the precise spatial arrangement of its functional groups, which is essential for constructing complex molecular architectures with specific biological or material properties. This chemical is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and by specialty chemical manufacturers exploring advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, or insecticides, where the fluorinated bicyclic core can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or other advanced materials that require rigid, fluorinated molecular components.
• Catalyst & Ligand Development: Employed in the creation of novel chiral catalysts or ligands for asymmetric synthesis, leveraging its defined stereochemistry.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical development.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-2-Ol, 5,6-Difluoro-, Acetate, (2-Endo,5-Exo,6-Exo)- (9Ci)
CAS No.	162427-13-6
Molecular Formula	C9H12F2O2
Molecular Weight	190.19 g/mol
Synonyms	(2-endo,5-exo,6-exo)-5,6-Difluorobicyclo[2.2.1]heptan-2-yl acetate; 5,6-Difluoronorbornan-2-endo-yl acetate (exo,exo); Bicyclo[2.2.1]heptan-2-ol, 5,6-difluoro-, acetate, (2-endo,5-exo,6-exo)-; (1R,2S,4S,5R)-5,6-Difluorobicyclo[2.2.1]heptan-2-yl acetate; endo-5,6-Difluoro-2-norbornyl acetate (exo,exo); Difluorinated norbornyl acetate intermediate; Fluorinated bicyclic acetate
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptan-2-Ol, 5,6-Difluoro-, Acetate, (2-Endo,5-Exo,6-Exo)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.