Description

Bicyclo[2.2.1]Heptan-2-Ol, 5,6-Difluoro-, Acetate, (Exo,Exo,Exo)- (9Ci) is a high-purity, stereochemically defined fluorinated bicyclic compound, serving as a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for complex organic synthesis. Its precise exo,exo,exo stereochemistry and fluorine substitution make it invaluable for developing novel active ingredients with enhanced metabolic stability and binding affinity. This compound is primarily sought by pharmaceutical R&D and fine chemical sectors for the production of targeted therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of fluorinated drug candidates, particularly in neurology and oncology.
• Agrochemical Research: Building block for developing novel fluorinated pesticides and herbicides with improved efficacy.
• Material Science: Monomer or precursor for specialty polymers and advanced materials requiring specific stereochemistry.
• Asymmetric Catalysis: Used as a ligand or a substrate in stereoselective catalytic reactions.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic and medicinal chemistry.
• Fluorine Chemistry: Serves as a model compound for studying the effects of fluorine atoms on the reactivity and conformation of bicyclic systems.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptan-2-Ol, 5,6-Difluoro-, Acetate, (Exo,Exo,Exo)- (9Ci)
CAS No.	162307-06-4
Molecular Formula	C9H12F2O2
Molecular Weight	190.19 g/mol
Synonyms	(1R,2S,4R)-5,6-Difluorobicyclo[2.2.1]heptan-2-yl acetate; (1R,2S,4R)-5,6-Difluoro-2-norbornyl acetate; exo,exo,exo-5,6-Difluoronorbornan-2-ol acetate; 5,6-Difluoro-2-norbornanol acetate (exo,exo,exo-); 162307-06-4; Bicyclo[2.2.1]heptan-2-ol, 5,6-difluoro-, acetate, (1R,2S,4R)-; (1R,2S,4R)-5,6-Difluoronorbornan-2-yl acetate
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptan-2-Ol, 5,6-Difluoro-, Acetate, (Exo,Exo,Exo)- (9Ci) adheres to stringent cGMP and ISO 9001 quality management standards to ensure batch-to-batch consistency and purity. Each lot undergoes comprehensive analytical characterization including HPLC for assay and impurity profiling, Chiral HPLC/GC for enantiomeric excess verification, and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.