Description

6-Chloro-1H-Indole-5-Carboxylic Acid Methyl Ester is a versatile indole-based building block, a key intermediate in advanced organic synthesis. Its value lies in providing a functionalized indole core, enabling the efficient construction of complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating advanced organic materials, including dyes, pigments, and electronic chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways involving halogenated indoles.
• Bioconjugation & Probe Development: The reactive ester and indole functionalities make it suitable for developing biochemical probes and conjugation linkers.

Basic Information

Product Name	6-Chloro-1H-Indole-5-Carboxylic Acid Methyl Ester
CAS No.	162100-83-6
Molecular Formula	C10H8ClNO2
Molecular Weight	209.63 g/mol
Synonyms	Methyl 6-Chloro-1H-indole-5-carboxylate; 6-Chloro-1H-indole-5-carboxylic acid methyl ester; 5-Carbomethoxy-6-chloroindole; 6-Chloroindole-5-carboxylic Acid Methyl Ester; 1H-Indole-5-carboxylic acid, 6-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Indole-5-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.