Description

5-Chloro-6-Methylindoline is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated indoline structure.
• Material Science Research: Serves as a building block for organic electronic materials, dyes, and photoactive compounds.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes for heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Chloro-6-Methylindoline
CAS No.	162100-57-4
Molecular Formula	C9H10ClN
Molecular Weight	167.63 g/mol
Synonyms	5-Chloro-6-methyl-2,3-dihydro-1H-indole; 6-Methyl-5-chloroindoline; 1H-Indole, 5-chloro-2,3-dihydro-6-methyl-; Indoline, 5-chloro-6-methyl-; 5-Chloro-6-methylindoline; 162100-57-4 (CAS); 5-Chloro-6-methyl-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Methylindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for production, ensuring traceability and consistency suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.