Description

1H-Indole,6-Fluoro-2,3-Dihydro-5-Methyl-(9Ci) is a fluorinated indoline derivative, a high-value synthetic intermediate prized for its unique molecular scaffold. This compound matters for its role in constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and synthesis of new chemical entities. The CAS number for this compound is 162100-50-7.

Application

This fluorinated building block is utilized in advanced organic synthesis across several high-tech industries.

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, due to the indoline core and fluorine atom's metabolic stability.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the fluorine substituent enhances biological activity and environmental persistence.
• Material Science: Serves as a monomer or functional group donor in the creation of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in fluorination chemistry and heterocyclic compound synthesis.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing novel fluorinated dyes and pigments with unique colorfastness and spectral properties.

Basic Information

Item	Detail
Product Name	1H-Indole,6-Fluoro-2,3-Dihydro-5-Methyl-(9Ci)
CAS No.	162100-50-7
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	6-Fluoro-5-methyl-2,3-dihydro-1H-indole; 5-Methyl-6-fluoroindoline; 6-Fluoro-5-methylindoline; 2,3-Dihydro-6-fluoro-5-methyl-1H-indole; Fluorinated indoline derivative; 6-Fluoro-5-methyl-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Our 1H-Indole,6-Fluoro-2,3-Dihydro-5-Methyl-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.