Description

Methylmercapto-2,3,4,6-Tetra-o-Benzyl-D-Mannopyranoside CAS NO 162061-34-9 is a sophisticated, fully protected thioglycoside derivative of D-mannose, serving as a critical chiral building block in synthetic organic chemistry. Its core value lies in its role as a versatile glycosyl donor, enabling the stereoselective construction of complex carbohydrate structures and glycoconjugates. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, particularly for the synthesis of novel therapeutics, diagnostic probes, and vaccine components.

Application

• Glycosylation Reactions: As a key glycosyl donor for the stereoselective synthesis of O-glycosides, S-glycosides, and C-glycosides.
• Pharmaceutical Intermediates: Critical building block for the development of carbohydrate-based drugs, antiviral agents, and antibiotic candidates.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other biologically active conjugates for immunological studies.
• Chemical Biology Probes: Enables the creation of labeled carbohydrate probes for studying carbohydrate-protein interactions and metabolic pathways.
• Oligosaccharide Assembly: A fundamental monomer in the iterative, solution-phase or solid-phase synthesis of complex oligosaccharides.
• Chiral Pool Synthesis: Serves as a source of chiral complexity for the asymmetric synthesis of non-carbohydrate natural products and bioactive molecules.

Basic Information

Product Name	Methylmercapto-2,3,4,6-Tetra-o-Benzyl-D-Mannopyranoside
CAS No.	162061-34-9
Molecular Formula	C35H38O5S
Molecular Weight	570.74 g/mol
Synonyms	Methyl 2,3,4,6-Tetra-O-benzyl-1-thio-α-D-mannopyranoside; 1-Thio-α-D-mannopyranoside, methyl 2,3,4,6-tetra-O-benzyl-; Methyl 1-Thio-2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside; 2,3,4,6-Tetra-O-benzyl-α-D-mannopyranosyl methyl sulfide; Tetra-O-benzyl-α-D-mannopyranosyl methylthioether; α-D-Mannopyranoside, methyl 2,3,4,6-tetra-O-benzyl-1-thio-; Methyl 1-thio-2,3,4,6-tetra-O-benzyl-α-D-mannoside
EINECS	Contact for details

Quality Control

Our production of Methylmercapto-2,3,4,6-Tetra-o-Benzyl-D-Mannopyranoside adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized by NMR (1H & 13C), HPLC, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, cool place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.