Description

4-Bromothiophene-2-Acetic Acid is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in providing a functionalized thiophene scaffold that enables the construction of complex molecules for research and development. This compound is primarily needed by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and the development of novel electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science Research: Used in the synthesis of conjugated polymers and organic semiconductors for applications in OLEDs, organic photovoltaics, and field-effect transistors.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-Bromothiophene-2-Acetic Acid
CAS No.	161942-89-8
Molecular Formula	C6H5BrO2S
Molecular Weight	221.07 g/mol
Synonyms	2-(4-Bromothiophen-2-yl)acetic Acid; (4-Bromo-2-thienyl)acetic Acid; 4-Bromo-2-thiopheneacetic Acid; 4-Bromothiophene-2-ylacetic Acid; 4-Bromo-2-thienylacetic Acid; 2-Thiopheneacetic acid, 4-bromo-; 161942-89-8
EINECS	Contact for details

Quality Control

Our 4-Bromothiophene-2-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.