Description

4-tert-Butoxycarbonylaminothiophene-3-Carboxylic Acid Methyl Ester CAS NO 161940-20-1 is a high-purity, protected thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing functionalized thiophene cores.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Serves as a precursor for organic electronic materials and functional polymers.
• Chemical Synthesis: A versatile reagent for introducing protected amine and ester functionalities onto thiophene rings in complex multi-step syntheses.
• Academic & R&D: Essential for methodological studies and exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	4-tert-Butoxycarbonylaminothiophene-3-Carboxylic Acid Methyl Ester
CAS No.	161940-20-1
Molecular Formula	C11H15NO4S
Molecular Weight	257.30 g/mol
Synonyms	Methyl 4-((tert-butoxycarbonyl)amino)thiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Boc-3ATME; 4-(Boc-amino)thiophene-3-carboxylic acid methyl ester; 4-(tert-Butoxycarbonylamino)thiophene-3-carboxylic Acid Methyl Ester; Methyl 4-(N-Boc-amino)thiophene-3-carboxylate; 4-(Boc-NH)-thiophene-3-COOMe
EINECS	Contact for details

Quality Control

Our 4-tert-Butoxycarbonylaminothiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.