Description

1-Stearoyl-2-Arachidonoyl Pc-D8 is a deuterated phospholipid, specifically a phosphatidylcholine (PC) isotopologue where eight hydrogen atoms are replaced by deuterium. This compound is a critical internal standard for the precise quantification of its non-deuterated counterpart in complex biological matrices using mass spectrometry. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and lipidomics fields who require high-purity, well-characterized reference materials to ensure analytical accuracy and data integrity in lipid metabolism and biomarker studies.

Application

• Quantitative Lipidomics: Serves as a stable isotope-labeled internal standard for the absolute quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (SAPC) in LC-MS/MS and GC-MS analyses.
• Biomedical Research: Used in studies of phospholipid metabolism, cell membrane dynamics, and the role of arachidonic acid-containing lipids in inflammatory pathways.
• Pharmaceutical Development: Employed in bioanalytical method development and validation for drug candidates targeting lipid-related disorders.
• Clinical Diagnostics: Facilitates the accurate measurement of specific phospholipids as potential biomarkers in plasma or tissue samples.
• Quality Control & Assurance: Acts as a reference material for calibrating analytical instruments and verifying the purity of related lipid products.

Basic Information

Product Name	1-Stearoyl-2-Arachidonoyl Pc-D8
CAS No.	161922-50-5
Molecular Formula	C46H78D8NO8P
Molecular Weight	832.15 g/mol (for D8 isotopologue)
Synonyms	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d8; SAPC-d8; Deuterated SAPC; 1-Octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine-d8; Phosphatidylcholine(18:0/20:4)-d8; PC(18:0/20:4)-d8; 1-Stearoyl-2-arachidonoyl Phosphatidylcholine-d8; AA-PC-d8
EINECS	Contact for details

Quality Control

Every batch of 1-Stearoyl-2-Arachidonoyl Pc-D8 is manufactured under controlled conditions and undergoes rigorous analytical characterization to ensure identity, purity, and isotopic enrichment. Our quality commitment includes comprehensive testing via NMR, HPLC, and mass spectrometry. A Certificate of Analysis (COA) detailing batch-specific results for purity, isotopic purity (D-enrichment), and solvent residues is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.