Description

2,4-Dimethoxybenzylbromide is a versatile and reactive benzyl bromide derivative, serving as a crucial alkylating agent and synthetic intermediate in advanced organic synthesis. Its value lies in its ability to introduce the 2,4-dimethoxybenzyl protecting group, which is selectively cleavable under mild acidic conditions, making it indispensable for complex molecule construction. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protecting groups in peptide and nucleoside chemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the dimethoxybenzyl moiety is required.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and photoinitiators used in polymer and coating industries.
• Protecting Group Reagent: Employed for the protection of alcohols, amines, and carboxylic acids in multi-step synthetic routes, especially in natural product synthesis.
• Material Science Research: Utilized in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology & Proteomics: Acts as a reagent for modifying biomolecules and in the development of chemical probes.

Basic Information

Product Name	2,4-Dimethoxybenzylbromide
CAS No.	161919-74-0
Molecular Formula	C9H11BrO2
Molecular Weight	231.09 g/mol
Synonyms	1-(Bromomethyl)-2,4-dimethoxybenzene; 2,4-Dimethoxybenzyl Bromide; (2,4-Dimethoxyphenyl)methyl Bromide; α-Bromo-2,4-dimethoxytoluene; DMB-Br; 2,4-Dimethoxy-α-bromotoluene; 2,4-Dimethoxybenzyl Bromide Reagent
EINECS	Contact for details

Quality Control

Our 2,4-Dimethoxybenzylbromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.